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Vaginal application of progesterone cream
Is it better to apply progesterone cream vaginally?
Let me start by saying that most creams you buy are not suitable for this because they contain chemical ingredients. Your vaginal skin is much too sensitive for them. Plus, it gets absorbed very quickly and efficiently vaginally. You don't want those chemical substances in your body. When you do apply vaginally, ensure it's a high-quality cream. Vaginal application really means applying internally, beyond the inner labia, between the uterus and the vagina.
I usually recommend applying where there are many capillaries, like the inner elbows or knees. Applying bioidentical progesterone cream to areas rich in capillaries (small blood vessels) can help with more efficient absorption of the hormone into the bloodstream. The capillaries in the mucous membranes are well vascularized and offer direct access to the bloodstream, allowing for faster and more effective absorption of the active ingredient than when applied to the skin.
The role of the liver in the absorption of progesterone
Applying where many small blood vessels are is important because you need to prevent the active substance from first passing through the liver before it is distributed into the bloodstream. This is called the "first-pass effect," and it can reduce the effectiveness of the active substance because the liver may break down part of the substance before it reaches the rest of the body. This is naturally strongest with something taken orally, like pills or liquids. But this effect is also slightly present when it's applied to the skin. Another consideration is when you apply where there is a lot of fat. Then it gets absorbed into the fat and doesn't work as well.
Benefits of vaginally applying bioidentical progesterone cream
Targeted delivery
Applying vaginally offers targeted delivery of progesterone directly into the vaginal tissue. This can improve the local hormonal balance in the genital area without significant influence on the rest of the body. From the vaginal/uterine balance, it impacts the rest of the body.
Reduced risk of skin irritation
Some people may experience skin irritation when applying hormonal creams to the skin. Vaginal application can reduce this risk, as vaginal tissue is generally less sensitive than the skin.
Faster absorption
Vaginal administration can lead to faster absorption of progesterone into the bloodstream, allowing it to start working quicker.
Specific gynecological benefits
Vaginal application of progesterone can be specifically useful for gynecological issues, such as managing vaginal dryness, treating endometriosis, and supporting uterine health.
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